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Abstract #1692

Magnetic Resonance Imaging Texture Analysis for Evaluating Radiation Induced Femoral Head Changes in Rectal Cancer after Radiotherapy

Jingjun Wu1
1Hangzhou Cancer Hospital, Hangzhou, China

Synopsis

Keywords: Bone, Bone, Radiation, MRI, Texture Analysis

Motivation: To promote a non-invasive method to evaluate the radiation induced femoral head changes.

Goal(s): To investigate the value of MRI texture analysis for evaluating radiation induced femoral head changes in rectal cancer patients after radiotherapy.

Approach: The texture parameters of T1WI, T2WI and DWI images were extracted in femoral head. And the differences of texture parameters before and after radiotherapy were compared.

Results: We found that when combined the texture parameters of T1WI, T2WI and DWI images, the diagnostic efficiency of femoral head changes was optimal with AUC of 0.85 (sensitivity,0.81; specificity,0.80).

Impact: MRI texture analysis may provide a non-invasive method to evaluate the radiation induced femoral head changes, providing imaging clues for monitoring the potential radiation-induced femoral head injury.

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