Keywords: Spectroscopy, Spectroscopy, MRSI, UHF, PRESS, FID
Motivation: Valuable in the preclinical realm, Magnetic Resonance Spectroscopic Imaging encounters issues with long acquisition time and low signal-to-noise ratio. Numerous excitation schemes allow for metabolic mapping.
Goal(s): The current study aims at comparing, with relevant quality metrics, preclinical application of two 1H-MRSI localization schemes at 14.1T: FID-MRSI and PRESS-MRSI.
Approach: Both FID and PRESS-MRSI datasets were acquired on the rodent brain in identical conditions (n=3) and processed using the same workflow for objective analysis.
Results: An increased coverage and SNR per unit of time were observed for FID-MRSI. Both methods reached similar quantitative results for two different brain regions.
Impact: Objective assessment of preclinical 1H-FID and 1H-PRESS-MRSI allows for exploration of their respective limitations and optimization of both localization schemes for different case studies found in preclinical research.
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