Keywords: Head & Neck/ENT, CEST & MT, Synthetic imaging, Sinonasal Lesions, APT
Motivation: Distinguishing between benign and malignant sinonasal lesions is crucial for determining the appropriate treatment regimen and predicting patient outcomes.
Goal(s): To evaluate the performance of synthetic MRI (SyMRI), combined with amide proton transfer (APT)-weighted MRI (APTw) in differentiating between malignant and benign sinonasal lesions.
Approach: Eighty patients with sinonasal lesions were underwent the SyMRI and ATPw scan and the quantitative parameters were analyzed.
Results: T1, T2, PD and APT values were significant between the benign and malignant groups. Combined SyMRI and APTw had the best diagnostic efficiency.
Impact: Combined the SyMRI with APTw would function as a quantitative and contrast-free approach, significantly enhancing the differentiation of benign and malignant sinonasal lesions. This method also helps overcome the limitations associated with the superficial nature of nasal endoscopic sampling.
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