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Abstract #2267

Accelerated 3D isotropic multi-echo UTE using CG-SENSE and Deep Learning Reconstruction for CT-like Imaging & Ultrashort T2* Mapping

Hung Phi Do1, Bekku Mitsuhiro2, Dawn Berkeley1, Brian Tymkiw1, Wissam AlGhuraibawi1, and Mo Kadbi1
1Canon Medical Systems USA, Inc., Tustin, CA, United States, 2Canon Medical Systems Corporation, Otawara, Japan

Synopsis

Keywords: Whole Joint, Bone

Motivation: MRI provides superior soft-tissue contrast, however, cortical bone and ultrashort-T2* tissues are invisible in routine clinical MRI. Multi-echo Ultrashort TE (mecho-UTE) may allow visualization and quantification of bone and ultrashort-T2* tissues, however, its acquisition time is often long.

Goal(s): We used CG-SENSE and Deep Learning Reconstruction (CG-SENSE+DLR) to accelerate mecho-UTE, making it clinically feasible.

Approach: 5-min, 3-min, and 2-min mecho-UTE scans were prospectively acquired and reconstructed with Gridding and CG-SENSE+DLR. Resolution, sharpness, and T2* were measured and compared.

Results: CG-SENSE+DLR allows 2- and 3-min mecho-UTE with improved resolution and sharpness compared to 5-min mecho-UTE with Gridding reconstruction.

Impact: Routine MRI and mecho-UTE enable comprehensive MSK imaging, providing soft-tissue contrast and visualization-and-quantification of bone and ultrashort-T2* tissues. CG-SENSE+DLR allows accelerated 2- and 3-minunte mecho-UTE, which would enable widespread clinical utilization to demonstrate the value of mecho-UTE compared to CT.

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Keywords