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Abstract #2489

Age-related assessment in a subset of SHIP data of intracranial vessel geometry from TOF MRI data

Dennis Wilk1, Patrick Winter1,2, Till Ittermann3, Sönke Langner4, Marie-Luise Kromrey5, and Susanne Schnell1,2
1Department of Medical Physics, Institute of Physics, University of Greifswald, Greifswald, Germany, 2Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 3Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany, 4Institute for Diagnostic and Interventional Radiology, Pediatric and Neuroradiology, University Medical Center Rostock, Rostock, Germany, 5Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany

Synopsis

Keywords: Blood Vessels, Blood vessels

Motivation: Intracranial vessels undergo age-related changes with increased risk of vascular pathologies such as atherosclerosis, or intracranial aneurysms. The occurrence probability of these pathologies could be indicated based on an altered vascular geometry.

Goal(s): The application of a geometric analysis to the vascular system of healthy volunteers of two age groups to study age-related changes in the geometry of intracranial arteries.

Approach: The analysis involved labeled centerline determination of intracranial arteries and calculating geometric parameters.

Results: Our study provided quantitative insights into age-related changes in intracranial artery geometry. Future research with larger, diverse samples can enhance the understanding and enable ML-based analyses.

Impact: The objective was to examine age-related changes in women of intracranial arteries by performing a geometric analysis on healthy volunteers. The quantitative evaluation enhances the comprehension of how intracranial artery geometry evolves with age.

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