Keywords: Spinal Cord, Spinal Cord
Motivation: The necessity to accurately delineate microstructural changes in the spinal cords of MS and NMOSD patients in vivo.
Goal(s): Assess if multiple b-tensor diffusion MRI data enhances the clinical utility of Micro Fractional Anisotropy (μFA) in distinguishing pathological variances in MS and NMOSD.
Approach: Comparative analysis of μFA values derived from planar tensor encoding data (DDE) and a combination of DDE with linear tensor encoding data was conducted.
Results: No significant μFA difference between MS and NMOSD was found, and additional linear tensor encoding data did not improve the results, highlighting the need for optimized imaging protocols.
Impact: This study elucidates the criticality of optimizing imaging protocols over merely aggregating data for precise diagnostic outcomes in MS and NMOSD. It prompts further investigation into refining imaging methodologies to uncover microstructural changes, enhancing diagnostic accuracy and subsequent patient management.
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