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Abstract #3097

Radiomics Model for Prognosis of Brainstem Stroke Based on Lesion and Surrounding Features

Kuang Fu1, Yun Wu1, Tianquan Xu1, Jia Wang1, Haonan Guan2, Shaonan Mi1, and Xin Yan1
1Harbin Medical University Second Affiliated Hospital, Harbin, China, 2GE Healthcare, MR Research China, Beijing, China

Synopsis

Keywords: Radiomics, Radiomics, Stroke

Motivation: Stroke is a major global health issue, necessitating early outcome prediction for optimal treatment. Brainstem stroke, often overlooked, requires dedicated predictive models due to its unique challenges.

Goal(s): Develop radiomics models to predict brainstem stroke outcomes, considering infarct edge and surrounding regions, improving prognosis, and simplifying clinical evaluation.

Approach: 474 patients were studied, and radiomics features were extracted from diffusion-weighted images. Machine learning models were trained using SVM, RF, KNN and AdaBoost algorithms.

Results: The RF model, based on the circle2 region, exhibited the highest performance (AUC=0.84). Models in the circle region outperformed core.

Impact: Our specialized radiomics models offer a valuable tool for personalized brainstem stroke treatment planning, potentially enhancing patient outcomes.

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