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Abstract #3302

T2*-weighted echo-planar imaging of the human brainstem and spinal cord at 7 Tesla with region-wise geometry, timing, and shim parameters

Jürgen Finsterbusch1, Ying Chu2, Christian Büchel1, and Falk Eippert2
1Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 2Max-Planck-Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

Synopsis

Keywords: fMRI Acquisition, fMRI, z-shim

Motivation: Combined fMRI acquisitions of human brainstem and cervical spinal cord helps to investigate their interaction, e.g., during pain processing.

Goal(s): To test whether combined T2*-weighted EPI of both regions is feasible at 7 Tesla.

Approach: EPI pulse sequence supporting region-wise geometry (FOV, slice thickness, voxel size), timing (echo spacing, echo time), and shim parameters (linear terms and frequency), and flip angles together with a region-wise shim algorithm extended to consider static third-order shim terms.

Results: A reasonable image quality could be obtained in both regions, but strategies to reduce ghosting artifacts in the spinal cord need to be investigated.

Impact: Being able to cover human brainstem and cervical spinal cord regions in a single EPI acquisition at 7 Tesla can help to investigate the interaction of both regions with improved spatial resolution.

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Keywords