(ISMRM 2024) Intratumoral Habitat and Peritumor Radiomics for Progression Risk Stratification of Patients with Soft Tissue Sarcoma: A Multicenter Study
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Abstract #3615

Intratumoral Habitat and Peritumor Radiomics for Progression Risk Stratification of Patients with Soft Tissue Sarcoma: A Multicenter Study

Hao-yu Liang1,2, He-xiang Wang2, Da-peng Hao2, Chuan-ping Gao2, Meng Zhang2, Qing Li3, Shun-li Liu2, Shi-feng Yang4, Feng Hou5, and Li-sha Duan6
1Department of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, Shanghai, China, 2Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, China, 3MR Collaboration Team, Siemens Healthineers, Shanghai, China, 4Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China, 5Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, China, 6Department of Radiology, The Third Hospital of Hebei Medical University, Shijiazhuang, China

Synopsis

Keywords: Diagnosis/Prediction, Skeletal

Motivation: Increasing the identification accuracy of patients with high risk of progression could help guide treatment decision in soft tissue sarcoma (STS).

Goal(s): To establish a radiomics nomogram that incorporated tumor habitat and peritumor features and validate its performance to predict tumor progression in patients with STS.

Approach: A nomogram combining radiomics based on intratumoral habitat and peritumorwith clinical information was established.

Results: This nomogram predicts tumor progression in STS patients and stratifies them according to the risk of progression.

Impact: Combining radiomics features derived from the intratumoral habitat and peritumoral region resulted in superior performance for predicting progression-free-survival in patients with STS, which is helpful for clinical decision making.

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Keywords

tumorprogressionpatientsnomogramfeaturesriskprediction