Keywords: Electromagnetic Tissue Properties, Tumor, Ionizing radiation
Motivation: Ionizing radiation produces ions inside the human body that can kill cancerous tissues by damaging DNA directly or creating charged particles that damage DNA.
Goal(s): Contrast mechanism of electrical conductivity is determined by the concentration and mobility of ions that make up tissues.
Approach: We applied MR-based conductivity imaging to mouse brain tumors to evaluate the responses in irradiated and non-irradiated tissues during the peri-irradiation period.
Results: MR-based conductivity images effectively showed acute response after irradiation in glial tumors.
Impact: High-frequency conductivity images can differentiate each brain tissues including viable tumors, tumor necrosis, and normal brain. It shows potential as a tool to differentiate the therapeutic effect of radiation by measuring absolute values and calculating percentage changes.
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