Keywords: Tumors (Post-Treatment), Diffusion/other diffusion imaging techniques, Glioma;recurrence
Motivation: Diffusion-weighted imaging and perfusion-weighted imaging have shown promising accuracy in differentiating glioma recurrence and treatment-related changes. Intravoxel incoherent motion (IVIM) MRI enables the simultaneous acquisition of diffusion and perfusion parameters, providing true diffusion and capillary perfusion in the tumor.
Goal(s): To evaluate the diagnostic performance of IVIM-derived parameters in glioma recurrence patients with DSC and 3DASL perfusion-weighted imaging.
Approach: The correlation between IVIM parameter and perfusion-MRI parameters was evaluated in regions of contrast enhancement with Pearson’s correlation analysis.
Results: ADC-F within T1-enhanced lesions positively correlated with relative cerebral blood volume (rCBV),nrCBF, and nCBF. Additionally,ADC-F was statistically significantly associated with rCBV and nrCBF.
Impact: IVIM has the same diagnostic efficacy for recurrent glioma with the perfusion-MRI parameters and can used as a reliable alternative diagnostic sequence for glioma recurrence.
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