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Abstract #3985

The prognostic value of amide proton transfer-weighted and intravoxel incoherent motion imaging for rectal adenocarcinoma.

Shiji Kan1, Bo Gao1, Pengyu Chen1, Yongjun Cheng2, and Kai AI3
1Affiliated Hospital of Guizhou Medical univeristy, Guiyang, China, 2Philips Healthcare, Shanghai, China, 3Philips Healthcare, Xi’an, China

Synopsis

Keywords: Cancer, Body, rectal cancer

Motivation: To improve the accuracy of rectal cancer staging via imaging techniques.

Goal(s): To explore the correlation between amide proton transfer (APT) imaging, intravoxel incoherent motion imaging (IVIM) quantitative parameters, and the pathological traits and prognostic markers of rectal adenocarcinoma.

Approach: Standard Magnetic resonance imaging (MRI), APT, and IVIM scans were performed on patients with suspected rectal cancer. Following this, APT and IVIM quantitative parameters were derived.

Results: Significant differences in D and D* values were observed across various T stages. However, no substantial variations in APT signal intensity (APTSI), D, D*, f were noted in different N stages, perineural invasion, and vascular invasion.

Impact: The research conducted has significant implications for the clinical staging of rectal cancer. By providing a more detailed and nuanced understanding of the disease's progression, it can aid in developing more precise and individualized treatment plans.

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Keywords