Keywords: Software Tools, Software Tools, preclinical, MRSI, spectroscopy
Motivation: Numerous software options exist for MRS processing, yet the preclinical domain lacks a harmonized multimodal toolbox featuring a graphical user interface (GUI).
Goal(s): Our goal was to create a harmonized toolbox tailored to preclinical MRS processing, with a special focus on addressing MRSI-related challenges.
Approach: The MRS4Brain Toolbox was designed to handle 1H and X nuclei data, and to allow brain segmentation of MRSI voxels in order to investigate brain regional differences.
Results: Fast and user-friendly brain MRSI segmentation and metabolic mapping were achieved, promoting the study of brain-regional differences.
Impact: The implementation of the open-source MRS4Brain Toolbox enables rapid and straightforward advanced preclinical MRS(I) data processing and quantification. It falls in line with the within- and across-site standardization effort launched by the MRS community.
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