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Abstract #4309

Stratified management of gestational hypertension: Superiority of functional magnetic resonance parameters over ultrasonography

Jing Deng1, Yuwei Cao1, Feifei Qu2, Aining Zhang1, Meng Zhao1, Xihu Mu1, Xin Zhou3, Yanglei Wu4, Jiacheng Song1, Feiyun Wu1, and Ting Chen1
1Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 2MR Research Collaboration, Siemens Healthineers, Shanghai, China, 3Department of Obstetrics & Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, 4MR Research Collaboration, Siemens Healthineers, Beijing, China

Synopsis

Keywords: Placenta, fMRI, gestational hypertension, placenta, preeclampsia, virtual magnetic resonance elastography

Motivation: Effective prenatal prediction of gestational hypertension (GH) can improve the clinical management of pregnant women at high risk of preeclampsia (PE) as pregnancy progresses.

Goal(s): To investigate the findings of placental virtual magnetic resonance elastography (vMRE), intravoxel incoherent motion (IVIM) parameters, and ultrasound examination to predict the progression of GH to PE.

Approach: We calculated vMRE and IVIM parameters and apparent diffusion coefficient and retrospectively performed ultrasound examinations. The differences in the aforementioned parameters were compared, and their predictive efficacy was evaluated.

Results: Patients with PE had higher placental stiffness and lower microcirculation.

Impact: Virtual magnetic resonance elastography and intravoxel incoherent motion comprise a vital complementary diagnostic method to conventional ultrasound screening for placental dysfunction in patients with high-risk hypertensive disorders in pregnancy, further improving the sensitivity and specificity of pregnancy screening.

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Keywords