Abstract #4432

Improved 3D-EPI with motion and FID-navigated field correction

Mustafa Utkur^1,2, Tess Wallace³, Tobias Kober^4,5,6, Sila Kurugol^1,2, and Onur Afacan^1,2

¹Radiology, Harvard Medical School, Boston, MA, United States, ²Computational Radiology Laboratory, Boston Children's Hospital, Boston, MA, United States, ³Siemens Medical Solutions USA, Inc., Boston, MA, United States, ⁴Advanced Clinical Imaging Technology, Siemens Healthcare International AG, Lausanne, Switzerland, ⁵Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁶LTS5, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Synopsis

Keywords: Artifacts, Neuro

Motivation: Previous studies have demonstrated field correction with 3D-EPI for fMRI and SWI, but ideal correction would account for both field inhomogeneities and motion.

Goal(s): We aimed to investigate the limits of simultaneous motion and field correction with 3D-EPI.

Approach: Our approach was to acquire in vivo data with controlled head motion. Volunteers were directed to rotate their heads 4-8 degrees and move left/right during scanning. We performed correction for field inhomogeneities using FID navigators after rigid motion registration.

Results: Analysis across varying rotation degrees showed the ability to successfully correct both motion and field distortions in 3D-EPI using FID navigators.

Impact: This simultaneous motion and field correction technique could enable high-resolution artifact-free 3D-EPI for fMRI studies. By correcting head motion and field inhomogeneities concurrently, the approach opens possibilities for investigating new research questions dependent on artifact-free imaging with substantial subject motion.

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