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Abstract #4530

Detection Efficiency of 18F-PSMA-1007 PET/CT and Multi-parameter MRI in Prostate Cancer and Its Correlation with Pathological Grade

Zhou Yunshu1, Chen Zhiqiang2, Zhang ruodi1, Liu Shili1, Chen Xiaohua1, Wang Aijun3, and Xiong Yuhui4
1Clinical medicine school of Ningxia Medical University, Yinchuan, China, 2Department of Radiology, The First Hospital Affiliated to Hainan Medical College, Haikou, China, 3Department of Radiology, General Hospital of Ningxia Medical University, Yinchuan, China, 4GE Healthcare MR Research, Beijing, China

Synopsis

Keywords: Preclinical Image Analysis, Tumor, prostate cancer

Motivation: The combination of MRI imaging and PSMA PET/CT imaging has attracted more and more attention.

Goal(s): Therefore, this study will compare the diagnostic value of 18F-PSMA-1007 PET/CT imaging and multi-parameter MRI alone and in combination with prostate cancer.

Approach: This study retrospectively collected the clinical, imaging and pathological data of 50 patients with prostate disease who underwent mp-MRI and 18F-PSMA-1007PET/CT examination in our hospital.

Results: We found that the combination of 18F-PSMA-1007 PET/CT and multi-parameter MRI can improve the diagnostic efficiency of prostate cancer. ADC value, SUVmax and SUVmax/ADC can distinguish between low-risk and medium-high-risk prostate cancer.

Impact: The diagnostic efficacy of combined multi-parameter MRI (ADC) and 18F-PSMAPET/CT (SUVmax) is better than that of ADC, SUVmax and SUVmax/ADC with higher sensitivity and specificity. The combination of these two imaging modalities can complement each other and improve the accuracy.

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Abstract

Keywords