Abstract #0145

Universal Pulses Enable a One-Hour Clinical Neuroimaging Protocol at Submillimeter Resolution on the NextGen 7T

Erica Walker^1,2, An T Vu^3,4, Pratik Mukherjee^3,4, Nicolas Boulant⁵, Vincent Gras⁵, Franck Mauconduit⁵, Aurélien Massire⁶, Philippa Krahn¹, Chunlei Liu¹, Alexander JS Beckett^1,2, and David A Feinberg^1,2

¹Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, United States, ²Advanced MRI Technologies, Sebastopol, CA, United States, ³Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, ⁴Radiology, San Francisco Veteran Affairs Health Care System, San Francisco, CA, United States, ⁵NeuroSpin, CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France, ⁶Siemens Healthineers, Courbevoie, France

Synopsis

Keywords: Epilepsy, Neuro

Motivation: Clinical imaging protocols of structural abnormalities stand to benefit from implementation of Universal Pulses (UP) in high-resolution whole-brain MRI at 7T.

Goal(s): To avoid the need for real-time patient-specific calibration and RF pulse tailored computations, UPs can provide data-trained pulse profiles tailored to sequence and coil while preserving efficacy across subjects.

Approach: Field maps were collected on 6 subjects and used as training data to design RF pulses for 3D anatomical sequences in a clinical scanning protocol for epilepsy patients.

Results: This work successfully demonstrates UP implementation for a clinical imaging protocol of adults and children on the Berkeley NextGen 7T scanner.

Impact: Universal Pulses provide a seamless solution to mitigate the RF field inhomogeneity problem for neuro MRI at 7T, enabling clinical populations to benefit from fast, high-resolution anatomical imaging without the need for dielectric pads.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.