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Abstract #0282

Grading the success of revascularisation surgery

Ece Su Sayin1, Akshaj Jonnalagadda2, James Duffin1, Julien Poublanc3, David Mikulis3, Joseph Fisher1,3, and Olivia Sobczyk3
1Physiology, University of Toronto, Toronto, ON, Canada, 2University College Dublin School of Medicine, Ireland, Ireland, 3University Health Network, Toronto, ON, Canada

Synopsis

Keywords: Blood Vessels, Vascular

Motivation: The comparison of outcomes of surgical revascularization to best medical therapy in steno-occlusive disease, is confounded by insufficient assessment of the efficacy of the surgical arm.

Goal(s): Our aim is to develop a graded CVR that reflects the hemodynamic status before and after surgical revascularization.

Approach: In 19 patients who had a CVR test before and after surgery, we identified and mapped the voxel-wise hemodynamic change in state in terms of 4 graded parameters.

Results: We identified markers showing a range of revascularization efficacy from minimal to considerable improvements in CVR.

Impact: Our CVR analysis grades the hemodynamic disruption, maps its distribution, and quantifies the efficacy of the intervention.

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Keywords