Abstract #0311

Reverse Encoding Distortion Correction (RDC) on DWI: Improving Image Quality and Diagnosis of Lymph Node Metastasis in Non-Small Cell Lung Cancer

Yoshiharu Ohno^1,2, Kaori Yamamoto³, Yuichiro Sano³, Masato Ikedo³, Masanori Ozaki³, Masao Yui³, Hiroyuki Nagata², Takahiro Ueda¹, Masahiko Nomura¹, Takeshi Yoshikawa¹, Daisuke Takenaka¹, and Yoshiyuki Ozawa¹

¹Diagnostic Radiology, Fujita Health University School of Medicine, Toyoake, Japan, ²Joint Research Laboratory of Advanced Medical Imaging, Fujita Health University School of Medicine, Toyoake, Japan, ³Canon Medical Systems Corporation, Otawara, Japan

Synopsis

Keywords: Lung, Cancer, Lymph node metastasis

Motivation: DWI with RDC technique (RDC DWI) might be more useful than conventional DWI (cDWI) to improve diagnostic performance of metastatic lymph node in non-small cell lung cancer (NSCLC) patients.

Goal(s): The goal was to determine the utility of RDC DWI to improve differentiation capability for lymph node metastasis as compared with cDWI and PET/CT in NSCLC patients.

Approach: This clinical study examined 69 metastatic and 69 no-metastatic lymph nodes by RDC DWI, cDWI and FDG-PET/CT, and diagnostic performance for lymph node were statistically compared among them.

Results: Specificity and accuracy of RDC DWI were significantly higher than those of cDWI and PET/CT (p<0.05).

Impact: RDC DWI has better potentials for improving distortion, image quality and diagnosis of lymph node metastasis as compared with cDWI and FDG-PET/CT in NSCLC patients.

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