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Abstract #0312

Clinical Application of Free-Breathing 3D Ultra-Short Echo Time Sequences to Detect Lung Nodules

Zhaoyan Zhou1,2, Zhiping Guo1,2,3, Yinghui Ge1,2, Xiaojing Kan1, Benkert Thomas4, Jing An5, and Mengzhu Wang6
1Fuwai Henan Hospital, Chinese Academy of Medical Sciences, Zhengzhou, China, 2Fuwai Hospital Central China, Zhengzhou University, Zhengzhou, China, 3Health Management Center of Henan Province, Zhengzhou, China, 4MR Application Predevelopment, Siemens Healthineers AG, Forchheim, Germany, 5Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, 6MR Research Collaboration, Siemens Healthineers Ltd, Beijing, China

Synopsis

Keywords: Lung, Lung, Lung MRI, UTE, Pulmonary nodule

Motivation: MSCT, used to examine lung nodules, poses ionizing radiation risks, hindering long-term follow-up; thus, MRI and ultra-short echo time (UTE) are preferable.

Goal(s): We compared UTE with MSCT to provide a non-radiative lung nodule examination protocol.

Approach: Two radiologists interpreted the UTE images; another radiologist matched them one-to-one with the MSCT results.

Results: UTE's sensitivity was 88% for detecting solid nodules ≥4 mm and 100% for subsolid nodules ≥8 mm. MSCT and UTE measured similar average nodule diameters. Lung-RADS v2022 classifications were consistent between both methods. UTE may be a radiation-free alternative for examining lung nodules.

Impact: UTE, an emerging non-radiative examination protocol, demonstrates great potential in detecting, diagnosing, and providing short-term follow-up of lung nodules and is poised to become an important tool for early screening and diagnosis of lung cancer.

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