Keywords: Tractography, Low-Field MRI
Motivation: Tractography affords advantage over volumetric segmentation as it separates areas of otherwise homogeneous contrast based on microstructural measures. Tract-based parameter mapping performed at ultra-low-field extends the utility of parametric maps to isolate functional regions, permitting quantitative studies in otherwise unscanned populations
Goal(s): We sought to implement a feasible tractometry scheme investigating multiple contrasts on a 0.064T commercial MR system
Approach: Corrected and denoised DWIs alongside quantitative T2 (qT2) maps were collected and processed to produce tract-specific measures of several diffusion parameters and qT2.
Results: Streamline parameter maps were found to agree with literature values of T2, MD and FA in a healthy participant.
Impact: Ultra-low-field MR systems offer unprecedented opportunity to access populations otherwise excluded from scanning by location or means. This work demonstrates that traditional high-field tractometry is possible at 0.064T within a feasible scan duration in healthy adults
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