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Abstract #0560

Simultaneous Bilateral T1, T2, and T1ρ Relaxation Mapping of Hip Osteoarthritis with 3D-MRI Fingerprinting

Anmol Monga1, Hector Lise de Moura1, Marcelo Wust Zibetti1, Thomas Youm2, Jonathan Samuels3, and Ravinder Regatte1
1Radiology, NYU Grossman School of Medicine, New York, NY, United States, 2Department of Orthopedic Surgery, NYU Grossman School of Medicine, New York, NY, United States, 3Department of Medicine, NYU Grossman School of Medicine, New York, NY, United States

Synopsis

Keywords: Osteoarthritis, MR Fingerprinting, Hip cartilage

Motivation: T1, T2 and T1ρ mapping using Magnetic Resonance Fingerprinting (MRF) is a promising approach to image Osteoarthritis (OA) in the hip joint.

Goal(s): Evaluate the feasibility of the 3D-MRF sequence to discriminate early hip OA patients from healthy subjects (HS).

Approach: We scanned 8 HS and 4 hip early OA patients. Dictionary matching is performed to estimate T1, T2, and T1ρ maps. Linear discriminant analysis (LDA) combines the parametric map values to improve OA detection.

Results: T1, T2, and T1ρ values in femur lateral compartment (hip joint) can distinguish early OA patients from HS. Combining the parameters using LDA improves early OA detection.

Impact: Our preliminary study demonstrates that T1, T2, and T1ρ values from 3D-MRF can potentially be used to detect early OA in the hip joint.

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Keywords