Abstract #0673

Design and evaluation of a 16-channel TUS/MR head coil

Lena Nohava¹, Onisim Soanca¹, Michael Obermann¹, Sarah Grosshagauer¹, Shota Hodono², Bernardo Campilho¹, Holger Hewener³, Steffen Tretbar³, Arno Schmitgen⁴, Sven Arnold⁴, Christian Windischberger¹, and Elmar Laistler¹

¹High Field MR Center, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, ²Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, Netherlands, ³Department of Ultrasound, Fraunhofer Institute for Biomedical Engineering IBMT, Sankt Ingbert, Germany, ⁴Localite GmbH, Bonn, Germany

Synopsis

Keywords: MR-Guided Focused Ultrasound, Focused Ultrasound, MR/TUS coil

Motivation: Transcranial ultrasound stimulation (TUS) offers promising non-invasive neuromodulation for treating neurological conditions. Integrating TUS with MRI requires a compatible coil that supports effective brain targeting and monitoring.

Goal(s): This study aims to design a 16-channel TUS/MR head coil (CITRUS coil) enabling precise, image-guided TUS within MRI.

Approach: The CITRUS coil incorporates transducer mounts and flexible coil segments, tested for TUS compatibility and MRI performance on phantom and in vivo.

Results: Preliminary results show that CITRUS maintains adequate MRI quality while supporting focused TUS, suggesting feasibility for combined TUS/fMRI applications.

Impact: The CITRUS coil advances TUS/fMRI capabilities, enabling focused ultrasound for neuromodulation. This development could expand clinical applications for non-invasive brain stimulation, addressing neurological and psychiatric conditions through precise, image-guided therapies.

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