Meeting Banner
Abstract #0763

The effects of cardiac gating, flow compensation, and robust fitting on diffusion kurtosis imaging of the kidneys

Nima Gilani1, Malika Kumbella1, Mary Bruno1, Jelle Veraart1, Dibash Basukala1, Hersh Chandarana1, and Eric E. Sigmund1
1Center for Advanced Imaging Innovation and Research, Department of Radiology, NYU Langone Health, New York, NY, United States

Synopsis

Keywords: DWI/DTI/DKI, DWI/DTI/DKI, Renal, microstructure

Motivation: The effects of cardiac gating and flow compensation on renal diffusion-weighted imaging have been investigated in the literature. Additionally, advanced diffusion kurtosis imaging (DKI) processing algorithms exist that use redundant information in directional diffusion-weighted acquisitions to derive better DKI fits.

Goal(s): Our goal was to understand and mitigate the impact of flow on DKI parameters to improve quantitative DKI.

Approach: We tested these methods on multidirectional DKI acquisitions of the kidneys which are affected by a combination of cardiac and breathing motion.

Results: These considerations mitigated artifact and flow effects on the kidney DKI and guided a regime for focused microstructural sensitization

Impact: Cardiac gating, flow compensation, and advanced processing pipelines mitigate artifacts and flow effects on diffusion kurtosis imaging of the kidney and allow more specific renal microstructural investigations.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords