Keywords: IVIM, IVIM, Ischemia, Perfusion
Motivation: A safe, non-contrast-enhanced method to detect bone marrow ischemia and perfusion is needed for imaging children with ischemic bone disorders such as Legg-Calvé-Perthes disease (LCPD).
Goal(s): To determine if intravoxel incoherent motion (IVIM) is sensitive in detecting localized regions of bone marrow ischemia and perfusion within the femoral head.
Approach: 3T MRI data from N=4 piglets with partial (25-75%) femoral head ischemia were retrospectively analyzed to evaluate and compare IVIM parameters in ischemic vs. perfused regions of the femoral heads as identified by gadolinium contrast-enhanced MRI (CE-MRI).
Results: IVIM detected decreased perfusion parameters in the ischemic vs. perfused regions identified by CE-MRI.
Impact: Our results provide additional evidence that IVIM can serve as a non-contrast-enhanced alternative to gadolinium CE-MRI in detecting regions of bone marrow ischemia and perfusion, with potential benefit for pediatric patients with ischemic bone disorders including LCPD.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords