Abstract #0776

Free-breathing 3D High-resolution Simultaneous Grey-blood Late Gadolinium Enhancement and MR Angiography at 3T

Dongyue Si¹, Simon J Littlewood¹, Michael G Crabb¹, Karl P Kunze^1,2, Claudia Prieto^1,3, and René M Botnar^1,3,4,5,6

¹School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, ³School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁴Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile, ⁵Institute of Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁶Institute for Advanced Study, Technical University of Munich, Garching, Germany

Synopsis

Keywords: Myocardium, Tissue Characterization

Motivation: CMR can provide multi-contrast images including late gadolinium enhancement (LGE) for myocardial tissue characterization and cardiac MR angiography (CMRA) for anatomical imaging. However, they are usually acquired separately in clinical routine.

Goal(s): To propose a 3D simultaneous Grey-Blood and Bright-blOOd phase SensiTive inversion recovery (GB-BOOST) sequence for one-stop imaging.

Approach: The proposed sequence acquires two interleaved 3D volumes with image navigator-based motion-correction in concert with inversion-recovery and T2-preparation pulses to obtain GB-LGE and CMRA simultaneously.

Results: GB-BOOST sequence can achieve whole-heart GB-LGE and CMRA with 1.2mm³ resolution in a single fast scan of approximately 10 mins with comparable performance as separately acquired images.

Impact: The proposed sequence can achieve co-registered 3D whole-heart grey-blood late gadolinium enhancement and cardiac MR angiography at a resolution of 1.2mm³ in a single fast scan of approximately 10 mins with comparable image quality as separately acquired images.

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