Abstract #0780

2D Adiabatic T1ρ Mapping of the Myocardium at 0.55T

Dongyue Si¹, Michael G Crabb¹, Simon J Littlewood¹, Karl P Kunze^1,2, Claudia Prieto^1,3, and René M Botnar^1,3,4,5,6

¹School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, ³School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁴Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile, ⁵Institute of Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁶Institute for Advanced Study, Technical University of Munich, Garching, Germany

Synopsis

Keywords: Myocardium, Low-Field MRI, Parametric mapping

Motivation: Adiabatic T1ρ mapping has recently shown promising results for contrast-free detection of scar and fibrosis but has not been demonstrated at lower-field strength, which could potentially make cardiac MRI more accessible and affordable.

Goal(s): To develop an accurate breath-held 2D adiabatic T1ρ mapping sequence at 0.55T.

Approach: The T1ρ-preparation was optimized for 0.55T in simulations and tested on phantoms and in-vivo with 5 healthy volunteers and 1 patient and compared with conventional mapping techniques.

Results: Preliminary 2D adiabatic T1ρ mapping results demonstrate good agreement in phantoms and promising results in-vivo.

Impact: Accurate 2D adiabatic T1ρ mapping in a single breath-hold scan at 0.55T for contrast-free detection of scar and fibrosis at lower-field.

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