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Abstract #0781

Simultaneous Myocardial T1, T2, T1ρ and Fat Fraction Mapping with Hybrid Dual-echo Cartesian Acquisition and Dictionary Matching

Zhenfeng Lyu1, Hongzhang Huang1, Haotian Hong1, Junpu Hu2, Liwei Hu3, Yumin Zhong3, Peng Hu1, and Haikun Qi1
1School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, China, Shanghai, China, 2United Imaging Healthcare, Inc., Shanghai, China, Shanghai, China, 3Department of Radiology, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, 1678 Dong Fang Road, Shanghai 200127, PR China, Shanghai, China

Synopsis

Keywords: Myocardium, Quantitative Imaging, Dictionary matching; Myocardial; T1; T2; T1ρ; Fat Fraction;

Motivation: Simultaneous cardiac parameters and fat quantification enables comprehensive myocardial tissue characterization. However, the water-fat MR fingerprinting techniques have complex image processing.

Goal(s): To develop a cardiac water-fat multi-parametric mapping technique with single-shot Cartesian acquisition and dictionary matching.

Approach: A novel Dixon-MultiMap sequence is proposed integrating the hybrid dual-echo Dixon readout into the multi-parametric mapping framework. The hybrid dual-echo data forms a four-echo dataset for accurate fat fraction and B0 estimations, and the derived B0 map is used as prior information for dual-echo water-fat separation of the multi-contrast images.

Results: Fat fraction and water-only T1, T2, T1ρ can be accurately estimated using Dixon-MultiMap.

Impact: The proposed Dixon-MultiMap achieves simultaneous multiple parameters and fat quantification with single-shot Cartesian acquisition and dictionary matching, which has simplified post-processing and holds great potential for clinical translation.

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