Keywords: Arrhythmia, Cardiomyopathy, Late gadolinium enhancement
Motivation: The predictive value of left ventricular late gadolinium enhancement (LV LGE) for arrhythmic events in arrhythmogenic right ventricular cardiomyopathy (ARVC) remains unclear.
Goal(s): To explore whether LV LGE serves as an independent predictor of the first episode of sustained ventricular arrhythmia (VA) and enhances the risk stratification of ARVC.
Approach: A retrospective analysis of 283 ARVC patients with baseline cardiovascular magnetic resonance (CMR) and no prior sustained VA was conducted, with long-term follow-up.
Results: LV LGE extent was independently associated with the first episode of sustained VAs in ARVC and further improve the risk stratification.
Impact: Our study demonstrated that LV LGE was independently associated with the first occurrence of sustained VAs in ARVC and could improve risk prediction of the proposed 5-year risk calculator, which might further refine the primary prevention strategies of the disease.
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