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Abstract #0786

LV Late Gadolinium Enhancement for the Primary Prevention of Ventricular Arrhythmias in Arrhythmogenic Right Ventricular Cardiomyopathy

Zhixiang Dong1, Yanyan Song1, and Shihua Zhao1
1MR Center, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, CHN, BEIJING, China

Synopsis

Keywords: Arrhythmia, Cardiomyopathy, Late gadolinium enhancement

Motivation: The predictive value of left ventricular late gadolinium enhancement (LV LGE) for arrhythmic events in arrhythmogenic right ventricular cardiomyopathy (ARVC) remains unclear.

Goal(s): To explore whether LV LGE serves as an independent predictor of the first episode of sustained ventricular arrhythmia (VA) and enhances the risk stratification of ARVC.

Approach: A retrospective analysis of 283 ARVC patients with baseline cardiovascular magnetic resonance (CMR) and no prior sustained VA was conducted, with long-term follow-up.

Results: LV LGE extent was independently associated with the first episode of sustained VAs in ARVC and further improve the risk stratification.

Impact: Our study demonstrated that LV LGE was independently associated with the first occurrence of sustained VAs in ARVC and could improve risk prediction of the proposed 5-year risk calculator, which might further refine the primary prevention strategies of the disease.

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