Keywords: Elastography, Elastography
Motivation: There exists a need for a noninvasive method capable of capturing skull-brain dynamics in vivo to provide accurate input parameters for computational models of traumatic brain injury.
Goal(s): We aimed to develop an accelerated fat-water imaging technique to quantify relative skull-brain displacement using magnetic resonance elastography (MRE).
Approach: Elastography with distributed generalized encoding was used to accelerate our previously developed fat-water MRE sequence to enable more extensive data collection in a single imaging session.
Results: This technique was able to simultaneously image skull and brain displacement with sufficient harmonic wave displacement to capture brain mechanical properties and bulk motion comparable to previous studies.
Impact: Quantifying relative skull-brain motion with the proposed sequence will help researchers define the transfer of skull-to-brain force transmission for ultimately determining regional variation in tissue displacement throughout the brain and the influence of different directions and frequencies of applied motion.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords