Keywords: Quantitative Imaging, Quantitative Imaging, T1 mapping, Myocardial T1, Subspace Reconstruction
Motivation: While$$$~T_1~$$$of the whole heart provides valuable diagnostic information, conventional methods are limited to single-slice acquisitions requiring multiple acquisitions and prolonging measurements due to repetitive breath-holds.
Goal(s): Development of rapid multi-slice $$$T_1~$$$mapping with high spatial resolution.
Approach: A radial single-shot IR-FLASH with slice-interleaved SMS-readout and total acquisition time of four seconds is combined with model-based reconstruction exploiting a linear subspace.
The technique was validated in phantom and in-vivo scans.
Results: Accuracy of $$$T_1$$$ in a phantom study were independent of simulated heart-rates with mean difference under$$$~8~ms$$$. Nine high-resolution short-axis myocardial$$$~T_1~$$$maps with whole-heart coverage were compared to Open-MOLLI and single-slice IR-FLASH showing a difference of$$$~38~ms$$$.
Impact: High resolution multi-slice $$$T_1$$$ quantification covering the whole-heart can be achieved within a short breath-hold of four seconds, which improves patient comfort, reduces motion artifacts, and improves the clinical feasibility of whole-heart $$$T_1$$$ mapping.
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