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Abstract #0875

A deep learning pipeline for lifespan cortical surface reconstruction, spherical mapping, and anatomical correspondence

Junjie Zhao1, Guoye Lin2,3, Xiaoyang Chen4, Sahar Ahmad2,3, and Pew Thian Yap2,3
1Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 2Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 3Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 4Department of Radiology, Duke University, Durham, NC, United States

Synopsis

Keywords: Gray Matter, Analysis/Processing, Registration, Cortical Surface Reconstruction

Motivation: Accurate lifespan cortical surface reconstruction (CSR) is important for understanding brain anatomy and longitudinal studies.

Goal(s): We present a deep learning pipeline that simultaneously reconstructs cortical surfaces, performs spherical mapping, and establishes anatomical correspondences across subjects.

Approach: Our model learns multi-scale velocity fields to iteratively deform a spherical template to match the inner or outer cortical surfaces, with a constraint that registers subjects to a reference surface for one-to-one vertex correspondence.

Results: Evaluation on a dataset spanning ages from 1 week to 90 years demonstrates that our model accurately predicts surfaces with inter-subject correspondence.

Impact: Our end-to-end pipeline offers a fast and accurate method for generating cortical surfaces, making it an efficient tool for surface-based analysis of cortical morphology.

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