Abstract #0909

Comparison of Capabilities for Regional Perfusion and Functional Changes among ECG- and PPG-Gated PREFUL MRIs and Dynamic CE-Perfusion MRI

Yoshiharu Ohno^1,2, Alicia Palomar-García³, Masao Yui⁴, Bruno Triaire⁴, Masanori Ozaki⁴, Kaori Yamamoto⁴, Yuichiro Sano⁴, Masato Ikedo⁴, Hiroyuki Nagata², Takahiro Ueda¹, Masahiko Nomura¹, Takeshi Yoshikawa¹, Daisuke Takenaka¹, and Yoshiyuki Ozawa¹

¹Diagnostic Radiology, Fujita Health University School of Medicine, Toyoake, Japan, ²Joint Research Laboratory of Advanced Medical Imaging, Fujita Health University School of Medicine, Toyoake, Japan, ³Canon Medical Systems Spain and Portugal, Madrid, Spain, ⁴Canon Medical Systems Corporation, Otawara, Japan

Synopsis

Keywords: Lung, Perfusion, Perfusion MRI

Motivation: PREFUL MRI with ECG and PPG as well as dynamic CE-perfusion MRI may evaluate regional perfusion and pulmonary functional changes in thoracic oncologic patients.

Goal(s): The goal was to determine the capability of three methods for regional perfusion and pulmonary functional loss assessments in thoracic oncology patients.

Approach: This clinical study examined 25 surgical treatment candidates by three methods, and each perfusion were correlated each other and with pulmonary function test results.

Results: There were significant correlations between each method (0.24≤r≤0.74, p<0.0001). There were significant correlations between function test results and perfusion determined from PW-MRIs with ECG (0.53≤r≤0.55, p<0.05) and PPG (0.54≤r≤0.66, p<0.05).

Impact: PW-MRI with ECG and PPG had equal to or better potential than that with dynamic CE-perfusion MRI for regional perfusion and pulmonary functional loss assessments in thoracic oncology patients with different underlying lung conditions.

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