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Abstract #1022

Preliminary study of multiparametric MRI in diagnosing acute kidney injury and chronic kidney disease without creatinine baseline in 3 months

Chenchen Hua1, Leting Zhou2,3, Muthuvel Jayachandran3, Ting Cai2, Shaowei Hao4, Xiangming Fang1, and Liang Wang2
1Diagnostic Radiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China, 2Nephrology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China, 3Nephrology and Hypertension, Mayo Clinic, Rochester, MN, United States, 4Siemens Healthineers Digital Technology(Shanghai) CO.,Ltd., Nanjing, China

Synopsis

Keywords: Kidney, Kidney, fMRI

Motivation: The majority of CKD patients and community-acquired AKI patients with abnormal creatinine levels are confused or cannot be distinguished timely at initial visit, due to lack of creatinine baseline within 3 months. Early detection for AKI patients is fundamental for timely therapeutic interventions.

Goal(s): We aim to using multiparametric MRI to diagnose AKI and CKD timely, and predict the prognosis of AKI.

Approach: Using DWI and T1 mapping to describe and understand the pathophysiology of AKI and CKD

Results: The combination of DWI and T1 mapping has potential clinical applicability in diagnosing AKI and CKD, and predicting the prognosis of AKI

Impact: The clinical application of multiparametric MRI for the early detection/prediction of AKI and long-term kidney injury is promising but challenging

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Keywords