Keywords: Heart Failure, Cardiovascular, Cardiac remodeling, Metabolic phenotypes, Obesity, Population imaging, Risk stratification
Motivation: Cardiac dysfunction patterns preceding cardiovascular events in different metabolic phenotypes remain poorly understood, limiting effective risk stratification in the general population despite rising obesity and metabolic disease rates.
Goal(s): To characterize cardiac adaptation patterns across metabolic phenotypes using UK Biobank cardiac MRI data and determine their association with long-term cardiovascular outcomes.
Approach: Analysis of cardiac structure, function, and clinical outcomes in 28,897 participants stratified by metabolic health and obesity status.
Results: Metabolic phenotypes showed distinct cardiac adaptations despite preserved ejection fraction, with both obesity and metabolic health status independently contributing to cardiovascular event risk.
Impact: This large-scale analysis reveals unique cardiac phenotypes across metabolic categories, providing new insights for early cardiovascular risk assessment in metabolically diverse populations.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords