Keywords: Neuro, Multimodal, MEG, Microstructure, Infant, Early Development, Diffusion MRI
Motivation: During human infancy, the brain undergoes rapid auditory and visual system development. However, the differential maturations of these systems remain largely unexplored.
Goal(s): This study aims to reveal the differential structural and functional developmental trajectories of auditory and visual systems during infancy.
Approach: We utilized multimodal structural and diffusion MRI, alongside auditory and visual task-based MEG, in a large infant cohort to assess the maturation and its structural-functional coupling.
Results: The MEG-based latency maturational trajectories suggest that visual system maturation may precede auditory system maturation. Additionally, cortical cytoarchitecture and auditory/visual development unfold differently, and structural maturation support the auditory and visual systems development.
Impact: Revealing the differential structural and functional maturation trajectories of the auditory and visual systems using multimodal MRI and task-based MEG in a large infant cohort may provide insights into both typical brain development and brain disorders.
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