Meeting Banner
Abstract #1066

Predicting lung cancer chemotherapy efficacy with extracellular volume fraction and intravoxel incoherent motion parameters

huizhi han1, wenxiu guo1, xiangtao lin1, huiting hao1, xiuchen li1, mimi tian1, hong ren1, jiaxiang xin2, and peng zhao1
1Shandong Provincial Hospital Affiliated to Shandong First Medical University, jinan, China, 2MR Research Collaboration Team, Siemens Healthineers Ltd, shanghai, China

Synopsis

Keywords: fMRI Analysis, Lung, Response evaluation criteria; cancer

Motivation: Early prediction of the chemotherapy response in lung cancer patients can help clinicians optimize treatment strategies.

Goal(s): To assess the value of intravoxel incoherent motion (IVIM) parameters and extracellular volume fraction (ECV) in predicting early chemotherapeutic efficacy in lung cancer.

Approach: Ninety-six lung cancer patients underwent IVIM and T1 mapping imaging before treatment. After two chemotherapy cycles, their ability to predict early chemotherapeutic efficacy in lung cancer was assessed by Response Evaluation Criteria in Solid Tumors (RECIST).

Results: IVIM and ECV were predictive for early chemotherapeutic efficacy in lung cancer, with ECV having a stronger association.

Impact: IVIM and ECV are potential tools for predicting early chemotherapy efficacy in lung cancer, creating new opportunities to refine initial treatment plans and improve patient prognosis, particularly for those who are resistant to chemotherapy.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords