Abstract #1088

Impact of Tumor Shape on Local Staging Accuracy Using VI-RADS in Bladder Cancer: Implications for MRI Protocol Selection

Yuki Arita^1,2, Thomas C. Kwee³, Keisuke Shigeta^4,5, Noam Nissan^1,6, Yenpo Lin⁷, Ryota Ishii⁸, Satoshi Masuyama⁹, Hiromi Edo¹⁰, Stefan J. Fransen³, Christian C. Roest³, and Jeeban P. Das¹

¹Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ²Radiology, Keio University, School of Medicine, Tokyo, Japan, ³Radiology, University Medical Center Groningen, Groningen, Netherlands, ⁴Dana-Farber Cancer Institute,, Harvard Medical School, Boston, MA, United States, ⁵Urology, Keio University School of Medicine, Tokyo, Japan, ⁶Radiology, Sheba Medical Center, Ramat Gan, Israel, ⁷Medical Imaging and Intervention, Chang Gung Memorial Hospital, Keelung City, Taiwan, ⁸Biostatistics, University of Tsukuba, Faculty of Medicine, Ibaraki, Japan, ⁹Internal Medicine, Osaka University, Shool of Medicine, Osaka, Japan, ¹⁰Radiology, National Defense Medical College, Saitama, Japan

Synopsis

Keywords: Urogenital, Bladder, VI-RADS

Motivation: Accurate local staging of bladder cancer is essential for guiding treatment decisions. However, the influence of tumor morphology on diagnostic performance of VI-RADS remains unclear.

Goal(s): To examine how the shape of bladder tumors influences the diagnostic accuracy of biparametric MRI (bpMRI), which combines T2WI and DWI, compared to multiparametric MRI (mpMRI), which includes T2WI, DWI, and dynamic contrast-enhanced MRI (DCE-MRI).

Approach: A retrospective analysis included 506 consecutive treatment-naïve patients with confirmed bladder urothelial carcinoma. Patients were grouped based on tumor shape, and diagnostic performance was evaluated using VI-RADS.

Results: bpMRI had significantly lower diagnostic performance for sessile/broad-based tumors compared to papillary tumors.

Impact: This study highlights the importance of considering tumor morphology in MRI protocols for bladder cancer. The use of DCE-MRI is crucial for accurate staging of sessile/broad-based tumors.

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