Abstract #1110

Application of Multi-Echo SSFP Sequences Using Multiple Pathways on Short T2 Mapping

Yiyun Dong¹, Paul Polak², Zheng Zhong³, Chenyang Zhao⁴, Junpu Hu⁵, Bochao Li⁶, Feng Fang³, and Yongquan Ye³

¹Physics, University of Washington, Seattle, WA, United States, ²Global Scientific Collaborations, United Imaging Healthcare, Houston, TX, United States, ³United Imaging Healthcare North America, Houston, TX, United States, ⁴Laboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, ⁵United Imaging, Shanghai, China, ⁶Biomedical Engineering, University of Southern California, Los Angeles, CA, United States

Synopsis

Keywords: Quantitative Imaging, Quantitative Imaging, T2 mapping, Short T2 mapping, 3D T2 sequence, Multi-pathway Multi-echo, SSFP

Motivation: T2 mapping is crucial for identifying abnormal tissues, while 3D clinically-approved T2 mapping sequence suffers from tradeoffs between the acquisition time and accuracy.

Goal(s): To improve and validate the accuracy of short T2 mapping using the 3D multi-pathway multi-echo (MPME) sequence and its variant.

Approach: The T2 calculation procedure from MPME sequence is incorporated with multi-dimensional integration (MDI) for improved accuracy. A dual-pathway dual-echo variant is developed for reducing the acquisition time.

Results: Phantom results demonstrate the short T2 mapping accuracy and precision of MPME and DPDE incorporated with MDI, as compared to the reference values.

Impact: Integrating MPME with MDI significantly improves its T2 mapping accuracy and precision, especially in the short T2 range, inspiring novel clinical applications that require high-speed 3D T2 mapping techniques.

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