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Abstract #1161

Cartilage shape-informed 3D gray level co-occurrence matrix analysis of DESS T2 maps

Veronika Janacova1,2, Pavol Szomolanyi1,3, Diana Sitarcikova1, Siegfried Trattnig1,4,5, and Vladimir Juras1
1High Field MR Centre, Medical University of Vienna, Vienna, Austria, 2CD Laboratory for MR Imaging Biomarkers (BIOMAK), Vienna, Austria, 3Institute of Measurement Science, Slovak academy of Sciences, Bratislava, Slovakia, 4Austrian Cluster for Tissue Regeneration, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria, 5Institute for Clinical Molecular MRI in the Musculoskeletal System, Karl Landsteiner Society,, Vienna, Austria

Synopsis

Keywords: Cartilage, Radiomics, Cartilage, T2 map, 3D

Motivation: To gain additional information about cartilage ultrastructure non-invasively from T2 maps.

Goal(s): To assess the stability of 3D GLCM features calculated based on cartilage shape, compared to the conventional 13 volumetric directions, using 3D DESS T2 map.

Approach: 5 volunteers underwent test-retest scan using 3D DESS sequence. From T2 maps, 20 GLCM features were calculated using 3 approaches: calculated in 13 volumetric directions and then averged; calculated along normal vectors of voxels; and along main axis projections to the tangent plane.

Results: Cartilage shape oriented calculation resulted in higher repeatability based on ICC3 coefficient.

Impact: This study demonstrates the high repeatability of cartilage shape informed 3D GLCM features. Since cartilage structure varies in directions perpendicular and parallel to the bone-cartilage interface, accurately assessing texture in these anatomically relevant orientations is clinically important.

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