Abstract #1229

Prediction of Long-term Motor Function Based on integrity of corticospinal tract in Ischemic Stroke after Intra-arterial Thrombectomy

Bing-Fong Lin¹, Wei Yang², Yen-Jun Lai³, Ting-Yi Lu¹, Shin-Lei Peng¹, and Chia-Feng Lu²

¹Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan, ²National Yang Ming Chiao Tung University, Taipei, Taiwan, ³Far Eastern Memorial Hospital, New Taipei City, Taiwan

Synopsis

Keywords: Stroke, Stroke, Intra-arterial Thrombectomy

Motivation: Intra-arterial thrombectomy (IAT) effectively removes the thrombus to restore cerebral blood flow. However, even if the thrombus is removed, the prior hypoxia may still lead to brain damage, resulting in motor deficits.

Goal(s): Poststroke motor function is highly associated with the integrity of white matter. We anticipated that early microstructural integrity may predict long-term motor function after IAT.

Approach: DTI and FMA were used to predict the motor function.

Results: The regression models show that adding FA, AD, RD, and ADC of CST as predictors could improve performance to an R²>0.705 and R²>0.566 (p<0.001) for predicting FMA-UE and -LE, respectively.

Impact: Early white matter integrity after IAT treatment can predict long-term motor function in ischemic stroke patients.

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