Keywords: Mesoscale: columns and layers, fMRI (task based)
Motivation: CBV and CBF based layer fMRI sequence methods suffer from relatively low sensitivity.
Goal(s): We aim to induce addtional CBV sensitivity through MT to boost overall VAPER-fMRI sensitivity.
Approach: We explored an innovative application of MT to induce a tissue-suppression-based VASO effect and integrate it with the VAPER technique.
Results: Both theoretical and experimental evaluation demonstrated approximately 30% enhancement in VAPER sensitivity with MT application compared to the original VAPER without MT.
Impact: We proposed an innovative MT-enhanced VAPER imaging sequence for layer fMRI that enhances sensitivity by 30% compared to traditional VAPER without MT, while maintaining superior laminar specificity without increasing acquisition time.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords