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Abstract #1275

Pulserver: an open-source Pulseq-based client-server framework for vendor agnostic, interactive MR sequence design

Matteo Cencini1,2, Kang Wang3, Sherry Huang4, Rolf F. Schulte5, Tim Sprenger5, Douglas C. Noll6, Michela Tosetti7, and Jon-Fredrik Nielsen6
1INFN, Pisa Division, Pisa, Italy, 2Imago7 Foundation, Pisa, Italy, 3GE HealthCare, Waukesha, WI, United States, 4GE HealthCare, Royal Oak, MI, United States, 5GE HealthCare, Munich, Germany, 6Functional MRI Laboratory, University of Michigan, Ann Arbor, MI, United States, 7IRCCS Stella Maris, Pisa, Italy

Synopsis

Keywords: Pulse Sequence Design, Pulse Sequence Design, Open Research; Software Tools

Motivation: Open-source vendor-agnostic sequence design frameworks (e.g., Pulseq) facilitate developing and sharing novel acquisition strategies but offer limited flexibility in prescription-time adjustments of imaging parameters (e.g., FOV, resolution) compared to vendor-proprietary toolkits.

Goal(s): To provide an open-source, vendor-agnostic software architecture for interactive sequence design.

Approach: We developed a high-level sequence representation based on Pulseq, enabling low-latency sequence design, along with a client-server architecture for interactive communication of imaging parameters from the scanner to the design server.

Results: Our framework enabled interactive design and execution of a Pulseq-based sequence directly from the scanner interface. Importantly, no external hardware was required.

Impact: Our framework bridges the low-access barrier of vendor-agnostic design frameworks like Pulseq with the interactive customizability of native vendor-provided sequences, enabling faster prototyping and deployment of novel techniques in clinical workflows.

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