Keywords: Tractography, Brain Connectivity, Hippocampus, Fimbria
Motivation: To investigate the connectome of the human hippocampus.
Goal(s): To elucidate intra-hippocampal connectivity, especially along the anterior-posterior axis.
Approach: To use mesoscale resolution (250 um isotropic) diffusion MR images to segment with high accuracy hippocampal substructures for tractography.
Results: Intra-hippocampal connectivity between subregions (head, body, tail) and subfields (CA1-3, dentate gyrus) was visualized and quantitated. Additionally, fibers from the fimbria were mapped onto the hippocampal substructures to provide a unique view of how intra- and extra-hippocampal networks interact.
Impact: Improving our conceptualization of intra- and extra-hippocampal connectivity is essential to further understanding of the structure-function relationship of hippocampal networks and how these are impacted by neurological and psychiatric conditions.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords