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Abstract #1475

Impact of Posture on Brain Volume Assessed with a Rotating 1.5T Cryogen-Free MRI in Healthy Individuals

Shiying Ke1, Yulin Wang1, Jichang Zhang1,2, Jie Zeng1, Shengyang Niu1, Chendie Yao1, Jianjun Zheng3, Thomas Meersmann4, and Chengbo Wang1
1Department of Electrical and Electronic Engineering, faculty of science and engineering, University of Nottingham Ningbo, Ningbo, China, 2Xingaoyi Medical Equipment Company, Ningbo, China, 3Department of Radiology, Ningbo No. 2 Hospital, Ningbo, China, 4Center for Life Science and Healthcare, University of Nottingham Ningbo, Ningbo, China

Synopsis

Keywords: Structural Connectivity, Brain, Spin MRI; Brain Structures; Volumetric Differences; Postural Effects

Motivation: This study aims to examine the clinical implications of postural effects on brain structure.

Goal(s): To investigate volumetric differences between upright and supine positions, providing a foundation for future research on how posture affects brain structure.

Approach: Thirty-two healthy volunteers were scanned using a cryogen-free 1.5T MRI scanner in supine and upright postures. The 3D T1-MP-RAGE brain images were segmented into 109 regions, and their corresponding volume changes were further evaluated.

Results: Most brain regions showed minimal volume change within a ±5% range, indicating structural stability across different postures. These findings provide a basis for future exploration of posture-related impacts on brain structure.

Impact: These findings on posture-related brain volume stability may inform future research on the clinical implications of postural effects, enhancing our understanding of brain structure integrity across different positions.

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