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Abstract #1518

Towards a hybrid low-cost MR-PET technology with therapeutic ultrasound capabilities.

Teresa Guallart-Naval1,2, Eduardo Pallás1,2, José Miguel Algarín1,2, Ruben Bosch1,2, Andrea Gonzalez-Montoro1,2, Marta Freire1,2, Joseba Alonso1,2, Fernando López1,2, Santiago Jiménez-Serrano1,2, Carlos de Alfonso1,2, Koldo Vidal1,2, Diana Andrés1,2, Juan José García1,2, José Luis Alonso-Ramos1,2, Alicia Carrión1,2, María José Rodríguez1,2, José María Benlloch1,2, Antonio Javier González1,2, and Francisco Camarena1,2
1Institute for Instrumentation in Molecular Imaging (i3M), CSIC, Valencia, Spain, 2Institute for Instrumentation in Molecular Imaging (i3M), Universitat Politècnica de València, Valencia, Spain

Synopsis

Keywords: Multimodal, Multimodal, Low-Field MRI, PET, Ultrasounds

Motivation: Hybrid medical devices can enhance diagnostic and therapeutic applications but are typically costly, large and inaccessible.

Goal(s): To develop a trimodal MR-PET-FUS system utilizing low-field MRI for a more affordable, accessible solution.

Approach: We integrated a 72 mT Halbach MRI scanner with PET and FUS technologies. We worked with a cylindrical phantom containing a copper-sulphate solution, gelatin, and a radioactive tracer. The system uses PET and MRI for imaging and FUS for heating.

Results: We have achieved simultaneous MR-PET imaging and successfully heated the phantom with FUS, demonstrating low-field MRI compatibility in a trimodal setup.

Impact: We present the first low-field MRI-integrated trimodal MR-PET-FUS system, enabling affordable, accessible devices. Having demonstrated simultaneous MR-PET acquisition and FUS heating, this work opens the path for cost-effective, multimodal diagnostics and treatment applications.

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Keywords