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Abstract #1633

Evaluating Cerebral Perfusion Changes in Acute Ischemic Stroke Patients After Enhanced External Counterpulsation Using ASL and IVIM Sequences

Xingjia Liu1, Sicong Wang2, Ao Zhang1, Qi Wang1, and Lanxiang Liu3
1The First Hospital of Qinhuangdao City Affiliated to Hebei Medical University, Qinhuangdao, China, 2GE Healthcare,MR Research China,Beijing, Beijing, China, 3The First Hospital of Qinhuangdao City, Qinhuangdao, China

Synopsis

Keywords: Blood Vessels, Arterial spin labelling, voxel-based incoherent motion

Motivation: There is a need for advanced MRI sequences to better assess brain perfusion changes in AIS patients following EECP treatment.

Goal(s): To use arterial spin labeling (ASL) and intravoxel incoherent motion (IVIM) MRI sequences to evaluate the short-term efficacy of EECP in AIS patients.

Approach: Correlation analysis was performed between changes in NIHSS scores and differences in ASL (PLD=1.5s, 2.5s) and IVIM parameters before and after EECP. ROIs were delineated, and quantitative differences in CBF (1.5s and 2.5s), D, D*, and f parameters were calculated.

Results: ASL and IVIM can evaluate the effect of EECP on cerebral perfusion in AIS patients.

Impact: ASL and IVIM effectively assess cerebral perfusion and collateral circulation in AIS patients. These imaging techniques offer a novel, non-invasive method for evaluating the efficacy of EECP treatment, providing valuable insights into treatment-related changes in brain perfusion and clinical outcomes.

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