Abstract #1665

Cardiac T1-mapping using Open-MOLLI at 3T: a repeatability study

Andreia S Gaspar¹, Thomas Küstner², Martin Schwartz³, Teresa M Correia^4,5, and Rita G Nunes¹

¹Instituto de Sistemas e Robótica–Lisboa and Departamento de Bioengenharia, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal, ²Department of Radiology, MIDAS.lab, University Hospital of Tuebingen, Tübingen, Germany, ³Section on Experimental Radiology, Diagnostic and Interventional Radiology, University Hospital of Tübingen, Tübingen, Germany, ⁴Centre of Marine Sciences UAlg, Universidade do Algarve, Faro, Portugal, ⁵School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Synopsis

Keywords: Quantitative Imaging, Acquisition Methods, T1 mapping, Open-MOLLI

Motivation: Myocardial T1-mapping was introduced to improve repeatability compared to qualitative measurements but extracted T1 values vary across scanners. The use of vendor-neutral techniques provides a robust and accessible approach for standardizing measurements, but their repeatability still needs to be assessed.

Goal(s): In this work we aim to study the repeatability of open-source myocardial T1 mapping (Open-MOLLI) at 3.0T and compare it to the vendor-implemented MOLLI sequence.

Approach: MOLLI and Open-MOLLI sequences were acquired in 15 subjects with repetition in each session to study T1 repeatability.

Results: Similar repeatability for in vivo T1 values was observed for MOLLI and Open-MOLLI at 3.0T.

Impact: The open-source myocardial T1 mapping (Open-MOLLI) was tested at 3.0T for repeatability with similar results to previous works at 1.5 T. This work shows that this sequence can be easily applied in inter-scanner reproducibility studies.

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