Meeting Banner
Abstract #1749

Pancreatic Fat Fraction as a Biomarker for Type 2 Diabetes Mellitus in Obese Individuals: An MRI-Based Study

Rui Zhang1, Yi Zhu2, and Yanhui Hao1
1The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China, 2Philips Healthcare, China, Beijing, China

Synopsis

Keywords: Pancreas, Pancreas

Motivation: To investigate the relationship between pancreatic fat deposition and the development of type 2 diabetes in obese individuals to understand its role in the pathogenesis of T2DM.

Goal(s): To assess pancreatic fat in obese patients with T2DM and normal controls using MR Dixon Quant technique to elucidate the role of ectopic fat deposition in pancreatic progression of T2DM in obese individuals.

Approach: Conducted a retrospective study using 3.0T MRI scans and MR Dixon Quant sequences to compare pancreatic fat fractions among obese T2DM patients, obese individuals without T2DM, and normal controls.

Results: Pancreatic fat fraction (PFF) was significantly higher in T2DM with obesity.

Impact: This research could guide early T2DM detection in obese patients and inform targeted therapeutic interventions.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords