Abstract #1759

Accelerated 2D Cine DENSE MRI using Golden-Angle Spiral Acquisition and Compressed Sensing Reconstruction

Shu-Fu Shih¹, Siyue Li¹, Yuxiao Wu^1,2, Sile Wang^1,2, Fei Han³, Holden H. Wu^1,2,4, Kim-Lien Nguyen^1,4,5,6, J. Paul Finn^1,7, and Xiaodong Zhong^1,2,4

¹Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States, ²Department of Bioengineering, University of California Los Angeles, Los Angeles, CA, United States, ³3Siemens Medical Solutions USA, Inc., Malvern, PA, United States, ⁴Physics and Biology in Medicine Graduate Program, University of California Los Angeles, Los Angeles, CA, United States, ⁵Division of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States, ⁶Division of Cardiology, VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States, ⁷Physics and Biology in Medicine Graduate Program, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States

Synopsis

Keywords: Myocardium, Myocardium, strain, DENSE MRI, spiral

Motivation: To accelerate the acquisition time of 2D spiral cine DENSE MRI for strain imaging.

Goal(s): To develop a golden-angle-ordered spiral cine DENSE sequence and a compressed sensing MRI reconstruction method and investigate the performance retrospectively undersampled datasets.

Approach: We used a compressed sensing model with constraints in the spatial domain and also along the cardiac phase domain for image reconstruction. We compared the image quality and the strain measurements from data acquired with linear ordering and golden-angle ordering.

Results: We demonstrated 1.5-fold accelerated 2D cine DENSE MRI. The proposed work may facilitate efficient DENSE data acquisition for strain imaging in clinical settings.

Impact: The proposed work may facilitate efficient DENSE data acquisition for strain imaging in clinical settings.

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